Ryan Reynolds' career began in 1990 when he starred as "Billy" in the Canadian-produced teen soap Hillside, distributed in the United States by Nickelodeon as Fifteen. As an adult, Reynolds starred in the National Lampoon movie Van Wilder and the American television series Two Guys, A Girl and a Pizza Place, playing medical student Michael "Berg" Bergen. In 1993-94 he had a recurring role in The Odyssey as Macro. He also cameoed in Harold & Kumar Go to White Castle as a nurse, appeared in The In-Laws with Michael Douglas and Albert Brooks, as well as the Canadian production Foolproof.
In 2005 he played a waiter named Monty in Waiting..., and as music executive Chris Brander in the romantic comedy Just Friends alongside Amy Smart and Anna Faris. Ryan Reynolds played the protagonist in the 2008 film Definitely, Maybe. He has also appeared in the second season finale of the television series Scrubs. In 2007, Ryan Reynolds guest-starred as Brendan's friend Hams in the episode "Douchebag in the City" of the TBS sitcom My Boys. In 2009, he portrayed Andrew Paxton, starring opposite Sandra Bullock, in The Proposal, and Mike Connell in Adventureland.
In a March 2005 interview, Ryan Reynolds spoke of his interest and involvement in a possible film adaptation of Deadpool with screenwriter David S. Goyer, as well as the possibility of playing the incarnation of The Flash known as Wally West in an adaption of the popular DC Comics character in the upcoming movie project. Reynolds portrayed Deadpool in the X-Men spinoff X-Men Origins: Wolverine and was announced to portray him again in a spin-off, Deadpool which is due out in 2013.
Ryan Reynolds portrayed superhero Hal Jordan/Green Lantern in Warner Bros.' film Green Lantern, released June 17, 2011 in 3D; this made him one of the few actors to headline in movies based on both Marvel and DC characters.
Ryan Reynolds also starred in the Spanish/Australian thriller Buried, which screened at the Sundance film festival.
Ryan Reynolds is scheduled to portray Nick Cruz in the Universal Pictures film adaptation of the Dark Horse Comics R.I.P.D. (Rest in Peace Department), which has a planned release in 2013.
In 2002 Ryan Reynolds began dating Canadian singer Alanis Morissette. The two announced their engagement in June 2004. In February 2007, representatives for Morissette and Reynolds announced that they had mutually decided to end their engagement. Morissette said her album Flavors of Entanglement was created out of her grief after the breakup.
On December 23, Ryan Reynolds filed for divorce and Johansson filed her response simultaneously in Los Angeles. the divorce was finalized on July 1, 2011.
In October 2008 Ryan Reynolds wrote for The Huffington Post regarding his plan to run the New York City Marathon for his father, who suffers from Parkinson's disease.
Ryan Reynolds appeared in People's Sexiest Man Alive lists in 2008 and 2009, and was awarded the top honor in 2010. In April 2011, he was ranked #15 on People's Most Beautiful 2011 list.